INSTINCT BIO TECHNICAL COMPANY HOLDINGS INC. — GroupGroup site (IR) →
Instinct Brothers Co., Ltd.

INSTINCT BROTHERS — Integrated regenerative stem cell cosmetics company

INSTINCT BROTHERS is an integrated company built around regenerative stem cell cosmetics — owning planning, manufacturing, and sales. We contribute to society across three domains: Beauty, Wellness, and Medicine.

Our Services→Contact us
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01BeautyRegenerative skincare
02WellnessInner & outer health
03MedicineClinical-grade science
Believe our Instinct.
Mission / 01

Mission

When everyone feels joy,that is when we create our greatest happiness.

Customers, partners, our team, and society — we keep refining our products and services around the joy of everyone we work with.

Believe our INSTINCT.

CEO Message / 02

Message from the CEO

Chairman & CEO Tomoki Nagano

Chairman & CEO

Tomoki Nagano

I have always trusted my instinct. Believe the spark, take it into action, and the path opens up — that conviction is at the heart of our name, INSTINCT.

INSTINCT BROTHERS began in the field of regenerative stem cell cosmetics and has built an integrated structure that owns product planning, manufacturing, and sales. Today we take on the challenge of contributing to society across three domains: Beauty, Wellness, and Medicine.

Our origin is simple. When everyone feels joy, that is when we create our greatest happiness. The smile of a customer, the trust of a partner, the pride of our team — each one is fuel that moves us forward.

Delivering joy to everyone, everywhere. With that purpose, INSTINCT BROTHERS will continue to trust our instinct and take on what's next.

Believe our INSTINCT.

Service / 03

What we do

From planning to manufacturing to sales — the speed and quality made possible by full vertical integration.

Index (01 — 04)
Regenerative Stem Cell Cosmetics — OEM / ODM
Beauty Manufacturing
01 — OEM / ODM

Regenerative Stem Cell Cosmetics — OEM / ODM

We provide OEM and ODM for cosmetics formulated with human stem cell culture extract. From concept and formulation through manufacturing and distribution, we support our clients' brand strategy end-to-end.

  • Brand differentiation through fully original formulations
  • Skincare, haircare, and bodycare across a wide range of categories
  • Flexible response to small lots and short lead times
  • Integrated with our group's manufacturing and raw-material network
Value Village — Our DtoC Portal
Value Village
02 — DtoC Portal

Value Village — Our DtoC Portal

Promotion and direct-to-consumer sales powered by our own portal site "Value Village," with influencer partnerships and full-service support for sales partners.

  • Storefront build, ops, analytics, logo and packaging design, ingredient sourcing
  • Founder and independence support (business planning, sales strategy, budgeting)
  • Initiatives that help balance family and work (SDG 8)
  • Launched the "MottainaE:CO" SDG initiative (2025)
Visit Value Village →
Medical Consulting & In-House Brand
Regenerative Medicine
03 — Medical

Medical Consulting & In-House Brand

We run planning and sales for our partner clinic "GENRÊVER CLINIC" and operate the in-house "GENRÊVER" brand. Corporate member of the Japanese Society for Regenerative Medicine.

  • Planning, sales, and promotion support for partner clinics
  • Product planning and operations for the in-house "GENRÊVER" brand (new launches in 2025)
  • Corporate member, Japanese Society for Regenerative Medicine
GENRÊVER CLINIC →
Global Business
Trade & Expansion
04 — Global

Global Business

We are expanding the GENRÊVER partner clinic network across Southeast Asia, acting as a trading partner to deliver Japanese technology, products, and services to local markets.

  • Export of regenerative stem cell cosmetics
  • Planning and rollout of partner clinics in Southeast Asia
  • Technology and service delivery with local partners
Our Brands / 04

Our Brands

Born from owning every step — planning, manufacturing, and sales. Every product is available on our portal, Value Village.

See all on Value Village →
Brand

GENRÊVER

The core in-house brand — a skincare line led by our serum.

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Brand

VIVÉA

From skincare to fragrance — a line designed for daily life.

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Brand

MANOROL

Illumirise C.B. MANOROL — a beauty line with regular POP UP events.

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Brand

HAKUA

A beauty line proposing entirely new experiences.

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News / 05
View all updates
value village

New release: "Vivéa Face Mask"

ALL

Golden Week holiday notice

INSTINCT BROTHERS

Launched SDG initiative "MottainaE:CO" (Value Village)

INSTINCT BROTHERS

Report: "manorol POP UP 2025"

value village

New from GENRÊVER: Malachite Boost Lotion

value village

Value Village division launched — building the future through sport

Source: instinct-biot.com · auto-synced

IR & timely disclosure: Disclosures related to NASDAQ listing preparation (SEC filings, business integration, etc.) are consolidated on the group (holding company) corporate site's IR page, and are not published here.

Contact / 06

Let's trust
the instinct, together.

We welcome inquiries on OEM/ODM, in-house brands, global expansion, and other partnerships. Reach out anytime below.

Email

info@instinct-bro.com

Group / IR

instinct-biot.com →

Group / 07

Through the Five Elements,
our group companies.

Centered on INSTINCT BIO TECHNICAL COMPANY, WOOD (Create) · FIRE (Broadcast) · EARTH (Foundation) · METAL (Craft) · WATER (Explore) — companies bound by the Eastern philosophy of Wu Xing, covering everything from raw materials to finished products.

View Group Structure →
木WOODCreate
火FIREBroadcast
土EARTHFoundation
金METALCraft
水WATERExplore
INSTINCT BROTHERS

木 / WOOD

INSTINCT BROTHERS

Core skincare business (this company)

— Current site

INSTINCT RAS

火 / FIRE

INSTINCT RAS

Branding & marketing

Visit site →

HIROKI GLOBAL

水 / WATER

HIROKI GLOBAL

Sourcing & R&D of specialty raw materials

Visit site →

ARTISANS PRODUCTION

金 / METAL

ARTISANS PRODUCTION

Manufacturing

Visit site →

instinct-biot.com

土 / EARTH

instinct-biot.com

Holding company · Corporate / IR

Visit site →